Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8pqw
Q-score: 0.342
Singh K, Lau CK, Manigrasso G, Gama JB, Gassmann R, Carter AP
Science (2024) 383 pp. eadk8544-eadk8544 [ DOI: doi:10.1126/science.adk8544 Pubmed: 38547289 ]
- Magnesium ion (24 Da, Ligand)
- Cytoplasmic dynein 1 intermediate chain 2 (68 kDa, Protein from Homo sapiens)
- Cytoplasmic dynein-1 bound to dynactin p150 and lis1 (Complex from Homo sapiens)
- Platelet-activating factor acetylhydrolase ib subunit beta (46 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Cytoplasmic dynein 1 heavy chain 1 (533 kDa, Protein from Homo sapiens)
- Dynactin subunit 1 (142 kDa, Protein from Sus scrofa)
GTPgammaS MT decorated with kinesin
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ysr
Q-score: 0.371
Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li G, Chu H, Wang HW
Nat Commun (2023) 14 pp. 5980-5980 [ Pubmed: 37749104 DOI: doi:10.1038/s41467-023-41615-w ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 15-protofilament gtpgammas-mt decorated with kinesin (220 kDa, Complex from Drosophila melanogaster)
- Tubulin alpha chain (49 kDa, Protein from Drosophila melanogaster)
- Tubulin beta-1 chain (50 kDa, Protein from Drosophila melanogaster)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8ixa
Q-score: 0.201
Diao L, Zheng W, Zhao Q, Liu M, Fu Z, Zhang X, Bao L, Cong Y
Acta Biochim.Biophys.Sin. (2023) 55 pp. 1551-1560 [ Pubmed: 37439022 DOI: doi:10.3724/abbs.2023130 ]
- Gmpcpp-alpha1a/beta2a-microtubule decorated with kinesin (Complex from Mus musculus)
- Tubulin alpha-1a chain (51 kDa, Protein from Mus musculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-1 heavy chain (41 kDa, Protein from Homo sapiens)
- Tubulin beta-2a chain (51 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8ixd
Q-score: 0.156
Diao L, Zheng W, Zhao Q, Liu M, Fu Z, Zhang X, Bao L, Cong Y
Acta Biochim.Biophys.Sin. (2023) 55 pp. 1551-1560 [ Pubmed: 37439022 DOI: doi:10.3724/abbs.2023130 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Gmpcpp-alpha1c/beta2a-microtubule decorated with kinesin (Complex from Mus musculus)
- Kinesin-1 heavy chain (41 kDa, Protein from Homo sapiens)
- Tubulin beta-2a chain (51 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Tubulin alpha-1c chain (50 kDa, Protein from Mus musculus)
GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8ixf
Q-score: 0.157
Diao L, Zheng W, Zhao Q, Liu M, Fu Z, Zhang X, Bao L, Cong Y
Acta Biochim.Biophys.Sin. (2023) 55 pp. 1551-1560 [ Pubmed: 37439022 DOI: doi:10.3724/abbs.2023130 ]
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Kinesin-1 heavy chain (41 kDa, Protein from Homo sapiens)
- Tubulin beta-2a chain (51 kDa, Protein from Mus musculus)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Tubulin alpha-4a chain (50 kDa, Protein from Mus musculus)
- Gmpcpp-alpha4a/beta2a-microtubule decorated with kinesin (Complex from Mus musculus)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
Alpha-synuclein fibril from spontaneous control
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8cyr
Q-score: 0.285
Zhou Y, Sokratian A, Viverette E, Borgnia M, Bartesaghi A, West A, Bouvette J, Dillard L
To Be Published
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha-synuclein fibril (33 MDa, Cellular component from Homo sapiens)
Structure of human cytoplasmic dynein-1 bound to two Lis1 proteins
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8dyu
Q-score: 0.339
Reimer JM, DeSantis ME, Reck-Peterson SL, Leschziner AE
eLife (2023) 12 [ Pubmed: 36692009 DOI: doi:10.7554/eLife.84302 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Platelet-activating factor acetylhydrolase ib subunit beta (46 kDa, Protein from Homo sapiens)
- Human cytoplasmic dynein-1 bound to two lis1 wd40 domains. (Complex from Homo sapiens)
- Cytoplasmic dynein 1 heavy chain 1 (380 kDa, Protein from Homo sapiens)
Non-muscle F-actin decorated with non-muscle tropomyosin 3.2
Resolution: 4.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ztd
Q-score: 0.36
Selvaraj M, Kokate SB, Reggiano G, Kogan K, Kotila T, Kremneva E, DiMaio F, Lappalainen P, Huiskonen JT
Cell Rep (2023) 42 pp. 111900-111900 [ DOI: doi:10.1016/j.celrep.2022.111900 Pubmed: 36586407 ]
- Non-muscle tropomyosin 3.2 (Cellular component from Homo sapiens)
- Non-muscle f-actin decorated with non-muscle tropomyosin 3.2 (Complex from Homo sapiens)
- Non-muscle tropomyosin 3.2 (11 kDa, Protein from Homo sapiens)
- Beta actin (non-muscle) (Cellular component from Homo sapiens)
- Actin, cytoplasmic 1 (41 kDa, Protein from human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of full-length Myosin Va in the autoinhibited state
Resolution: 4.78 Å
EM Method: Single-particle
Fitted PDBs: 7yv9
Q-score: 0.189
Niu F, Liu Y, Sun K, Xu S, Dong J, Yu C, Yan K, Wei Z
Sci Adv (2022) 8 pp. eadd4187-eadd4187 [ DOI: doi:10.1126/sciadv.add4187 Pubmed: 36490350 ]
- Myosin va and calmodulin complex (630 kDa, Complex from Mus musculus)
- Calmodulin-1 (16 kDa, Protein from Mus musculus)
- Unconventional myosin-va (212 kDa, Protein from Mus musculus)
The nucleosome-bound human PBAF complex
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7y8r
Q-score: 0.172
Wang L, Yu J, Yu Z, Wang Q, Li W, Ren Y, Chen Z, He S, Xu Y
Nat Commun (2022) 13 pp. 7644-7644 [ Pubmed: 36496390 DOI: doi:10.1038/s41467-022-34859-5 ]
- Swi/snf complex subunit smarcc2 (133 kDa, Protein from Homo sapiens)
- Phd finger protein 10 (56 kDa, Protein from Homo sapiens)
- Nucleosome-bound human pbaf complex (Complex from Homo sapiens)
- Protein polybromo-1 (184 kDa, Protein from Homo sapiens)
- Dna (213-mer) (65 kDa, DNA from Homo sapiens)
- Unknown (1 kDa, Protein from Homo sapiens)
- Histone h3 (15 kDa, Protein from Homo sapiens)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e member 1 (46 kDa, Protein from Homo sapiens)
- At-rich interactive domain-containing protein 2 (197 kDa, Protein from Homo sapiens)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily d member 1 (58 kDa, Protein from Homo sapiens)
- Unknown (2 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Actin-like protein 6a (47 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Unknown (2 kDa, Protein from Homo sapiens)
- Transcription activator brg1 (184 kDa, Protein from Homo sapiens)
- Dna (213-mer) (65 kDa, DNA from Homo sapiens)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily b member 1 (44 kDa, Protein from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
- Unkown (1 kDa, Protein from Homo sapiens)
- Histone h2a type 1-c (14 kDa, Protein from Homo sapiens)
- Histone h2b (13 kDa, Protein from Homo sapiens)
- Bromodomain-containing protein 7 (74 kDa, Protein from Homo sapiens)
- Unknown (8 kDa, Protein from Homo sapiens)
- Actb protein (fragment) (41 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)